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Product Details
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- Molecular Formula: C18H22O
- Molecular Weight: 254.372
- Vapor Pressure: 5.59E-07mmHg at 25°C
- Melting Point: 130-131.5 °C
- Refractive Index: 1.592
- Boiling Point: 400.2 °C at 760mmHg
- PKA: 14.03±0.40(Predicted)
- Flash Point: 180.6 °C
- PSA: 20.23000
- Density: 1.111 g/cm3
- LogP: 4.41440
Estratetraenol(Cas 1150-90-9) Usage
|
Definition |
ChEBI: A 3-hydroxy steroid that is obtained by formal dehydration at the 17-position of estradiol. |
InChI:InChI=1/C18H22O/c1-18-9-2-3-17(18)16-6-4-12-11-13(19)5-7-14(12)15(16)8-10-18/h2,5,7,9,11,15-17,19H,3-4,6,8,10H2,1H3/t15-,16-,17+,18+/m1/s1
1150-90-9 Relevant articles
A pharmaceutical composition containing 2-hydroxy-7-methyl octahydrophenanthrene derivative as an estrogen receptor ligand or a pharmaceutically acceptable salt thereof as an effective component
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Paragraph 0050; 0064; 0065, (2017/01/02)
Provided are a compound represented by c...
Method of increasing alertness by administration of a vomeropherin, and vomeropherin-emitting alarm devices
-
, (2008/06/13)
A method of increasing alertness in an i...
ESTRENE STEROIDS AS NEUROCHEMICAL INITIATORS OF CHANGE IN HUMAN HYPOTHALAMIC FUNCTION AND RELATED PHARMACEUTICAL COMPOSITIONS
-
, (2008/06/13)
The invention relates to a method of alt...
Androstane steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods
-
, (2008/06/13)
The invention relates to a method of alt...
1150-90-9 Process route
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-
55105-93-6
estrone p-toluenesulfonylhydrazone
-
-
1150-90-9
1,3,5(10) ,16-estratetraen-3-ol
| Conditions | Yield |
|---|---|
|
With
n-butyllithium; sodium chloride; ammonium chloride; sodium hydrogencarbonate;
In
tetrahydrofuran; hexane;
|
70%
|
|
With
n-butyllithium; sodium chloride; ammonium chloride; sodium hydrogencarbonate;
In
tetrahydrofuran; hexane;
|
70%
|
|
With
n-butyllithium; sodium chloride; ammonium chloride; sodium hydrogencarbonate;
In
tetrahydrofuran; hexane;
|
70%
|
|
With
n-butyllithium; sodium chloride; ammonium chloride; sodium hydrogencarbonate;
In
tetrahydrofuran; hexane;
|
70%
|
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-
(E)-N'-((8R,9S,13S,14S)-3-hydroxy-13-methyl-7,8,9,11,12,13,15,16-octahydro-6H-cyclopenta[A]phenanthrene-17(14H)-ylidene)-4-methylbenzenesulfonohydrazide
-
-
1150-90-9
1,3,5(10) ,16-estratetraen-3-ol
| Conditions | Yield |
|---|---|
|
With
n-butyllithium;
In
tetrahydrofuran;
at -78 - 20 ℃;
for 13h;
Inert atmosphere;
|
77%
|
1150-90-9 Upstream products
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50-28-2
estradiol
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53-16-7
Estrone
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55105-93-6
estrone p-toluenesulfonylhydrazone
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23880-57-1
(8S,9S,13R,14S)-3-(benzyloxy)-13-methyl-7,8,9,11,12,13,14,15-octahydro-6H-cyclopenta[a]phenanthrene
1150-90-9 Downstream products
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1316291-21-0
(8R,9S,13S,14S)-3-(benzyloxy)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-16,17-diol
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23880-57-1
(8S,9S,13R,14S)-3-(benzyloxy)-13-methyl-7,8,9,11,12,13,14,15-octahydro-6H-cyclopenta[a]phenanthrene