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Imazalil

  • Cas number:35554-44-0
  • purity:99%
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1.What is the Imazalil ?

Imazalil is a systemic fungicide with protective and curative action. It is used for the control of a wide range of fungal diseases on fruit, vegetables and ornamentals, powdery mildew on roses and storage diseases of citrus fruit, pome fruit, bananas and seed potatoes. It is also used as a seed dressing, for control of diseases of cereals (particularly Fusarium and Helminthosporium spp.), and it is particularly active against benzimidazole-resistant strains of plant-pathogenic fungi.

1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethan-1-ol
24155-42-8

1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethan-1-ol

3-chloroprop-1-ene
107-05-1

3-chloroprop-1-ene

1-[2-(2,4-dichlorophenyl)-2-(2-propenyloxy)ethyl]-1H-imidazole
35554-44-0

1-[2-(2,4-dichlorophenyl)-2-(2-propenyloxy)ethyl]-1H-imidazole

Conditions
Conditions Yield
1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethan-1-ol; With potassium hydroxide; In water; dimethyl sulfoxide; at 20 ℃; for 1h;
3-chloroprop-1-ene; In water; dimethyl sulfoxide; at 30 ℃; for 3h; Solvent; Temperature;
95.6%
1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethan-1-ol; With potassium hydroxide; In water; dimethyl sulfoxide; at 20 - 35 ℃; for 1h;
3-chloroprop-1-ene; In water; dimethyl sulfoxide; at 35 - 40 ℃; Reagent/catalyst;
68%
1H-imidazole
288-32-4

1H-imidazole

3-chloroprop-1-ene
107-05-1

3-chloroprop-1-ene

2,2',4'-trichloroacetophenone
4252-78-2

2,2',4'-trichloroacetophenone

1-[2-(2,4-dichlorophenyl)-2-(2-propenyloxy)ethyl]-1H-imidazole
35554-44-0

1-[2-(2,4-dichlorophenyl)-2-(2-propenyloxy)ethyl]-1H-imidazole

Conditions
Conditions Yield
2,2',4'-trichloroacetophenone; With tris(triphenylphosphine)ruthenium(II) chloride; acetic acid; triethylamine; at 70 ℃; for 9h;
1H-imidazole; With N,N-dimethyl acetamide; sodium hydroxide; at 50 - 100 ℃; for 5h;
3-chloroprop-1-ene; at 105 ℃; for 6h; Reagent/catalyst; Solvent;
64.4%

2.What is the CAS number for Imazalil ?

The CAS number of Imazalil is 35554-44-0.

More information of Imazalil 35554-44-0 are:

CAS?Number

35554-44-0

Density

1.23 g/cm3

Melting Point

52.7 °C

Boiling Point

448.5 °C at 760 mmHg

Flash Point

225.1 °C

Vapor Pressure

1.58 x l0-4 Pa (20 °C)

Refractive Index

1.5680 (estimate)

HS CODE

29332900

PSA

27.05000

LogP

4.13380

Pka

6.53 (weak base)

3.What are another words for Imazalil ?

Synonyms?for?Imazalil 35554-44-0:Enilconazole;CGA 41333;1H-Imidazole,1-[2-(2,4-dichlorophenyl)-2- (2-propenyloxy)ethyl]-;Deccozil S 75;1-[2-(2,4-dichlorophenyl)-2-prop-2-enoxy-ethyl]imidazole nitrate;1-[20(2,4-dichlorophenyl)-2-(2-propenyloxy)ethyl]-1H-imidazole;lmazalil;1-[2-(allyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole;(±)-l-[2-(2,4-dichlorophenyl)-2-(2-propenyloxy)ethyl]-l H-imidazole;

4.What is the molecular formula of Imazalil?

The chemical formula of ?Imazalil is?C14H14Cl2N2O which containing 14 Carbon atoms,14 Hydrogen atoms,2 Chlorine atoms,2 Nitrogen atoms and 1 Oxygen atoms,and the molecular weight of??Imazalil?is 297.184.

5.What is Imazalil (35554-44-0) used for?

Imazalil is an imidazole fungicide that inhibits ergosterol biosynthesis. Imazalil inhibits the growth of various fungi in vitro including P. italicum, A. niger, U. maydis, B. alii, and C. cucumerinum in a pH-dependent manner (MICs = 0.005-2 μg/ml at pH 7). It inhibits S. cerevisiae, but not rat liver microsomal, cytochrome P450 enzymes (CYPs; IC50s = 0.088 and 80 μM, respectively), as well as aromatase CYP19 from human placental microsomes (IC50 = 0.34 μM). Imazalil activates the murine pregnane X receptor (PXR) in a concentration-dependent manner in a cell-based reporter assay. It increases hepatic CYP3A11 and CYP2B10 mRNA levels in mice when administered at a dose of 100 mg/kg. Imazalil also increases Ki-67-positive nuclei in liver sections and hepatic MCM2 mRNA levels, markers of cell proliferation, in mice when co-administered with the murine constitutive androstane receptor (mCAR) agonist TCPOBOP . Formulations containing imazalil have been used to control fungal infection in agriculture.

InChI:InChI=1/C14H14Cl2N2O/c1-2-7-19-14(9-18-6-5-17-10-18)12-4-3-11(15)8-13(12)16/h2-6,8,10,14H,1,7,9H2

Relevant articles related to Imazalil:

Article

Source

Enilconazole bulk drug preparation method

-

Paragraph 0039-0055, (2019/11/20)

Design and synthesis of novel imidazole derivatives as potent inhibitors of allene oxide synthase(CYP74)

Oh, Keimei,Murofushi, Noboru

, p. 3707 - 3711 (2007/10/03)

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Imazalil

CAS:35554-44-0

Purity:99%

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